Web9 jun. 2024 · In treatment naïve patients, the single-arm phase 2 KEYNOTE-427 trial treated patients with pembrolizumab, noting a median PFS of 7.1 months (95% CI 5.6-11.0) and a median OS not reached (95% CI 31.2 to not reached) 7. Dr. McKay notes that the KEYNOTE-564 trial is a randomized double-blind placebo-controlled phase 3 clinical trial … Web20 mei 2024 · KEYNOTE-427 (NCT02853344) is a single-arm, open-label, phase 2 study of pembro monotherapy in patients (pts) with advanced clear cell RCC (cohort A) and NCC …

Renal Cell Carcinoma: AK104, Axitinib的临床试验-临床试验注册中 …

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Pembrolizumab Monotherapy in Non-Clear Cell Renal Cell Carci ...

Web16 feb. 2024 · The results of this randomized, phase 3 trial of patients with previously untreated advanced renal-cell carcinoma showed that treatment with pembrolizumab … WebASCO GU 2024: Results from KEYNOTE-427 Cohort Bb - First-line Pembrolizumab Monotherapy for Advanced Non-Clear Cell RCC San Francisco, CA (UroToday.com) … Web15 dec. 2024 · Monotherapy data of pembrolizumab was submitted and reviewed from KEYNOTE-427, ... randomized open label study of axitinib compared with sorafenib in the first-line treatment of patients with advanced RCC . In KEYNOTE-426, the ORR for pembrolizumab in combination with axitinib (59%; 95% CI, 54–64) was superior to ORRs … provence grand large fos sur mer