Fucosyltransferase activity
WebApr 13, 2024 · With adequate serum concentration of antiepileptic drugs, the epilepsy symptoms in many patients still cannot be controlled well. The alteration of glycosyltransferase has obvious influence on the pathogenesis of epilepsy. In this study, we focus on the diagnostic and prognostic value of fucosyltransferase 8 (Fut8) on epilepsy … A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. The acceptor substrate can be another sugar such as the transfer of a fucose to a core GlcNAc (N-acetylglucosamine) sugar as in the … See more Glycosyltransferase family 10 CAZY GT_10 comprises enzymes with two known activities; galactoside 3(4)-L-fucosyltransferase (EC 2.4.1.65) and galactoside 3-fucosyltransferase (EC 2.4.1.152). … See more FUT1; FUT2; FUT3; FUT4; FUT5; FUT6; FUT7; FUT8; FUT9; FUT10; FUT11; See more Robust fucosyltransferase activity discourages bacterial adherence in the urethra of women. This is also mediated by the presence of few bacterial adhesion sites in the bladder and urethra. Women with these receptors who do not have mucosal secretion … See more • fucosylation See more • Fucosyltransferases at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more
Fucosyltransferase activity
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Webfucosyltransferase activity Ontology molecular_function Synonyms None Alternate IDs None Definition Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. Source: GOC:ai Comment None History See term history for GO:0008417 at QuickGO WebJan 1, 2024 · α-1,3-fucosyltransferase crystal structure. Sun et al. revealed three X-ray crystal structures of α-1,3-fucosyltransferase, containing the FUT·GDP-Fuc and FUT·GDP complexes from Helicobacter pylori. The mammalian α-1,3-FUTs have a homologous nucleotide binding site with H. pylori, which comprises an N-terminal catalytic domain, a …
WebJun 28, 2016 · The plant cell wall is a complex network of polysaccharides made up of cellulose, hemicelluloses and pectins. Xyloglucan (XyG), which is the main … WebDiverse members of the Bacteroidetes phylum have general protein O-glycosylation systems that are essential for processes such as host colonization and pathogenesis. Here, we analyzed the function of a putative fucosyltransferase (FucT) family that is widely encoded in Bacteroidetes protein O-glycosylation genetic loci. We studied the FucT orthologs of …
WebAcceptor-dependent fucosyltransferase activity was calculated from the difference between these two curves (Fig. 5A; curve labeled “fucosyltransferase activity”). Initial rate data were calculated from a 5-min reaction, and established that the optimum conditions for the coupled reaction were 37 °C, ... WebThere are two genes (FUT1 and FUT2) which encode galactoside 2-L-fucosyltransferase. They are expressed in a tissue-specific manner with expression restricted to cells of …
WebAug 1, 2008 · Changes in enzyme activity and the expression levels of alpha (1,6)fucosyltransferase [alpha (1,6)FT] have been reported in certain types of malignant transformations. To develop a better understanding of the role of alpha (1,6)FT in human colorectal carcinoma (CRC), we analysed the enzyme activity in healthy and tumour …
WebCOS-7 cells transfected with theSe wA385T allele had weak, but detectable, α(1,2)fucosyltransferase activity, with an acceptor substrate pattern similar to the wild type FUT2 gene. Comparative kinetic studies from cell extracts with mutatedSe wA385T and wild type FUT2 alleles gave similarK m values, but less enzyme activity was present in ... horse on hill englandWebExpression of alpha- (1,3)-fucosyltransferases which synthesize sialyl Le (x) and sialyl Le (a), the carbohydrate ligands for E- and P-selectins,in human malignant cell lines. Transcripts of alpha- (1,3)-fucosyltransferases in human epithelial cancer and leukemia cell lines were analyzed by Northern…. horse on its hind legs• Cameron HS, Szczepaniak D, Weston BW (Aug 1995). "Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms". The Journal of Biological Chemistry. 270 (34): 20112–22. doi:10.1074/jbc.270.34.20112. PMID 7650030. • Reguigne-Arnould I, Couillin P, Mollicone R, Fauré S, Fletcher A, Kelly RJ, Lowe JB, Oriol R (1995). "Relative positions of two clusters of human alpha-L-fucosyltransferases in 1… horse on keyboards