WebMar 10, 2005 · Methanobactin is an extracellular, copper-binding chromopeptide from the methane-oxidizing bacterium, Methylosinus trichosporium OB3b, believed to be involved in copper detoxification, sequestration, and uptake. Although small (1217.2 Da), methanobactin possesses a complex three-dimensional macrocyclic structure with … WebAbstract. Cyclic peptides (CPs) belong to an interesting class of peptides that have been widely studied over the past decades. This class of peptides has been applied in …
Marine-derived chromopeptide A, a novel class I HDAC …
WebPc. chromopeptide have been demonstrated for geometric iso-mers (E-configurated) prepared from all-Z-configurated Pr chromopeptides and phycocyanin chromopeptides (11). Similar properties also were reported for E-configurated bilindiones (12-17). It was concluded that the chromophore of the Pfr pep- WebJan 23, 2024 · Chromopeptide A is a novel class I HDAC inhibitor. (A) Chemical structures of chromopeptide A and FK228. (B) Selectivity profiling on HDAC enzymes of … dx3s receiver
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WebSep 16, 2016 · Chromopeptides, obtained by pepsin digestion, were purified and identified by tandem mass spectrometry. These chromopeptides demonstrated significant antioxidant, Cu2 + -chelating and anti-cancer activities. 2. Materials and methods 2.1. C-phycocyanin and phycocyanobilin purification and quantification WebNov 23, 2024 · Due to their intrinsic characteristics, self-assembled peptide micro/nanostructures are capable to load both hydrophobic and hydrophilic drugs, and they are suitable to achieve a triggered drug delivery at disease sites by inserting in their structure's stimuli-responsive moieties. WebSep 10, 2004 · We present evidence of analogous molecules for copper transport from methane-oxidizing bacteria, represented here by a small fluorescent chromopeptide (C 45 N 12 O 14 H 62 Cu, 1216 daltons) produced by Methylosinus trichosporium OB3b. The crystal structure of this compound, methanobactin, was resolved to 1.15 angstroms. crystal michelle collins ky